Prenatal weight and regional body composition trajectories and neonatal body composition: The NICHD Foetal Growth Studies.

ABSTRACT:

Background

Gestational weight gain (GWG) and anthropometric trajectories may affect foetal programming and are potentially modifiable.

Objectives

To assess concomitant patterns of change in weight, circumferences and adiposity across gestation as an integrated prenatal exposure, and determine how they relate to neonatal body composition.

Methods

Data are from a prospective cohort of singleton pregnancies (n = 2182) enrolled in United States perinatal centres, 2009-2013. Overall and by prepregnancy BMI group (overweight/obesity and healthy weight), joint latent trajectory models were fit with prenatal weight, mid-upper arm circumference (MUAC), triceps (TSF) and subscapular (SSF) skinfolds. Differences in neonatal body composition by trajectory class were assessed via

SUBMITTER: Widen EM 

PROVIDER: S-EPMC9924063 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature