Application of quantitative proteomics to discover biomarkers for tick resistance in cattle.

ABSTRACT:

Introduction

Breeding for tick resistance is a sustainable alternative to control cattle ticks due to widespread resistance to acaricidal drugs and the lack of a protective vaccine. The most accurate method used to characterise the phenotype for tick resistance in field studies is the standard tick count, but this is labour-intensive and can be hazardous to the operator. Efficient genetic selection requires reliable phenotyping or biomarker(s) for accurately identifying tick-resistant cattle. Although breed-specific genes associated with tick resistance have been identified, the mechanisms behind tick resistance have not yet been fully characterised.

Methods

This study applied quantitative proteomics to examine the differential abundance of serum and skin proteins using samp

SUBMITTER: Raza A 

PROVIDER: S-EPMC9924087 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature