Impact of anxiety and depression on progression to glaucoma among glaucoma suspects.

ABSTRACT:

Aims

To assess the impact of anxiety and depression in the risk of converting to glaucoma in a cohort of glaucoma suspects followed over time.

Methods

The study included a retrospective cohort of subjects with diagnosis of glaucoma suspect at baseline, extracted from the Duke Glaucoma Registry. The presence of anxiety and depression was defined based on electronic health records billing codes, medical history and problem list. Univariable and multivariable Cox proportional hazards models were used to obtain HRs for the risk of converting to glaucoma over time. Multivariable models were adjusted for age, gender, race, intraocular pressure measurements over time and disease severity at baseline.

Results

A total of 3259 glaucoma suspects followed for an average of 3.60 (

SUBMITTER: Berchuck S 

PROVIDER: S-EPMC9924953 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature