Association Between Receipt of General Anesthesia During Childhood and Attention Deficit Hyperactive Disorder and Neurodevelopment.

ABSTRACT:

Background

There are inconsistent reports regarding the association between general anesthesia and adverse neurodevelopmental and behavioral disorders in children.

Methods

This nationwide administrative cohort study included children born in Korea between 2008 and 2009, and followed until December 31, 2017. The cohort included 93,717 participants who received general anesthesia with endotracheal intubation (ETI) who were matched to unexposed subjects in a 1:1 ratio. General anesthesia was defined by National Health Insurance Service treatment codes with intratracheal anesthesia, and the index date was the first event of general anesthesia. The primary outcome was attention deficit hyperactive disorder (ADHD), which was defined as at least a principal diagnosis of 10th revisi

SUBMITTER: Song JY 

PROVIDER: S-EPMC9925326 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature