Association between hypotension and myocardial injury in patients with severe trauma.

ABSTRACT:

Purpose

During resuscitation of patients with severe trauma, guidelines recommend permissive hypotension prior to surgical bleeding control. However, hypotension may be associated with reduced organ perfusion and multiple organ dysfunction, e.g. myocardial injury. The association between hypotension and myocardial injury in trauma patients is underexplored. We hypothesized that hypotension is associated with myocardial injury in this population.

Materials and methods

This retrospective study included patients ≥ 18 years suffering from severe trauma [defined as Injury Severity Score (ISS) ≥ 16] that were treated in the emergency department resuscitation room between 2016 and 2019. Primary endpoint was the incidence of myocardial injury defined as high-sensitive troponin T > 1

SUBMITTER: Stroda A 

PROVIDER: S-EPMC9925499 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature