Blood pressure and kidney function in neonates and young infants with intrauterine growth restriction.

ABSTRACT:

Background

Intrauterine growth restriction (IUGR) has been associated with changes in kidney anatomy, nephrogenesis and the vascular system, resulting in secondary arterial hypertension and kidney damage in adulthood. Here, we compare routine clinical and metabolic parameters between IUGR and non-IUGR study participants in the neonatal and early infant period.

Methods

A total of 39 IUGR and 60 non-IUGR neonates were included during an 18-month study period. We compared blood pressure, serum creatinine (SCr), urea nitrogen (BUN), urinary albumin, α-1-microglobulin, transferrin, immunoglobulin G and total protein excretion in spontaneous urine normalized by urine creatinine level during the hospital stay.

Results

There were no significant differences in mean values of b

SUBMITTER: Heuchel KM 

PROVIDER: S-EPMC9925571 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature