Associations of the Serum Total Carbon Dioxide Level with Long-Term Clinical Outcomes in Sepsis Survivors.

ABSTRACT:

Introduction

Sepsis is characterized by a dysregulated host response to infection that leads to multiple organ dysfunction and often complicated with metabolic acidosis. However, the associations between serum total carbon dioxide level (TCO₂) and long-term clinical outcomes in sepsis survivors remains unknown.

Methods

A total of 7212 sepsis survivors aged ≥ 20 years who were discharged from January  1, 2008 to December 31, 2018 were included in our analyses. The sepsis survivors were further divided into high TCO₂ (≥ 18 mmol/L) and low TCO₂ (< 18 mmol/L) groups, comprising 5023 and 2189 patients, respectively. The following outcomes of interest were included: all-cause mortality, myocardial infarction, ischemic stroke, hospitalization for he

SUBMITTER: Yang CH 

PROVIDER: S-EPMC9925627 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature