Lithium use in childhood and adolescence, peripartum, and old age: an umbrella review.

ABSTRACT:

Background

Lithium is one of the most consistently effective treatment for mood disorders. However, patients may show a high level of heterogeneity in treatment response across the lifespan. In particular, the benefits of lithium use may vary in special clinical conditions. The aim of this study was to test this hypothesis by conducting an umbrella review on the efficacy and safety of lithium in childhood and adolescence, peripartum and old age.

Methods

We applied the Preferred Reporting Items for Systematic Reviews and Meta-analyses criteria (PRISMA) to identify systematic reviews/meta-analyses on the efficacy and/or safety of lithium in mood disorders in special clinical conditions: (i) childhood and adolescence; (ii) peripartum (pregnancy, postpartum and lactation); (iii)

SUBMITTER: Janiri D 

PROVIDER: S-EPMC9925650 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature