Prognostic value of ¹⁸F-FDG PET/CT-based radiomics combining dosiomics and dose volume histogram for head and neck cancer.

ABSTRACT:

Objectives

By comparing the prognostic performance of ¹⁸F-FDG PET/CT-based radiomics combining dose features [Includes Dosiomics feature and the dose volume histogram (DVH) features] with that of conventional radiomics in head and neck cancer (HNC), multidimensional prognostic models were constructed to investigate the overall survival (OS) in HNC.

Materials and methods

A total of 220 cases from four centres based on the Cancer Imaging Archive public dataset were used in this study, 2260 radiomics features and 1116 dosiomics features and 8 DVH features were extracted for each case, and classified into seven different models of PET, CT, Dose, PET+CT, PET+Dose, CT+Dose and PET+CT+Dose. Features were selected by univariate Cox and Spearman correlation coefficients, a

SUBMITTER: Wang B 

PROVIDER: S-EPMC9925656 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature