Influence of county-level geographic/ancestral origin on glioma incidence and outcomes in US Hispanics.

ABSTRACT:

Background

Glioma incidence is 25% lower in Hispanics than White non-Hispanics. The US Hispanic population is diverse, and registry-based analyses may mask incidence differences associated with geographic/ancestral origins.

Methods

County-level glioma incidence data in Hispanics were retrieved from the Central Brain Tumor Registry of the United States. American Community Survey data were used to determine the county-level proportion of the Hispanic population of Mexican/Central American and Caribbean origins. Age-adjusted incidence rate ratios and incidence rate ratios (IRRs) quantified the glioma incidence differences across groups. State-level estimates of admixture in Hispanics were obtained from published 23andMe data.

Results

Compared to predominantly Caribbean-o

SUBMITTER: Walsh KM 

PROVIDER: S-EPMC9925707 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature