Postacute COVID-19 Syndrome: ¹²⁹Xe MRI Ventilation Defects and Respiratory Outcomes 1 Year Later.

ABSTRACT: Background In individuals with postacute COVID-19 syndrome (PACS) and normal pulmonary function, xenon 129 (¹²⁹Xe) MRI ventilation defects, abnormal quality-of-life scores, and exercise limitation were reported 3 months after infection; the longitudinal trajectory remains unclear. Purpose To measure and compare pulmonary function, exercise capacity, quality of life, and ¹²⁹Xe MRI ventilation defect percent (VDP) in individuals with PACS evaluated 3 and 15 months after COVID-19 infection. Materials and Methods In this prospective study, participants with PACS aged 18-80 years were enrolled between July 2020 and August 2021 from two quaternary care centers. ¹²⁹Xe MRI VDP, diffusing capacity of lung for carbon monoxide (Dlco), spirometry, oscillometry, 6-minut

SUBMITTER: Kooner HK 

PROVIDER: S-EPMC9926501 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature