Echocardiographic assessment of Xenopus tropicalis heart regeneration.

ABSTRACT:

Background

Recently, it was reported that the adult X. tropicalis heart can regenerate in a nearly scar-free manner after injury via apical resection. Thus, a cardiac regeneration model in adult X. tropicalis provides a powerful tool for recapitulating a perfect regeneration phenomenon, elucidating the underlying molecular mechanisms of cardiac regeneration in an adult heart, and developing an interventional strategy for the improvement in the regeneration of an adult heart, which may be more applicable in mammals than in species with a lower degree of evolution. However, a noninvasive and rapid real-time method that can observe and measure the long-term dynamic change in the regenerated heart in living organisms to monitor and assess the regeneration and repair status in this mode

SUBMITTER: Lv L 

PROVIDER: S-EPMC9926761 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature