Are HOMA-IR and HOMA-B good predictors for diabetes and pre-diabetes subtypes?

ABSTRACT:

Background

To investigate the association between the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and Homeostasis Model Assessment of Beta-cell function (HOMA-B) with the incidence of diabetes and pre-diabetes subtypes.

Methods

A total of 3101 normoglycemic people aged 20-70 years were included in the 6-year follow-up study. Multinomial logistic regression was used to calculate the incidence possibility of isolated Impaired Fasting Glucose (iIFG), isolated Impaired Glucose Tolerance (iIGT), Combined impaired fasting glucose & impaired glucose tolerance (CGI), and Diabetes Mellitus (DM) per standard deviation (SD) increment in HOMA-IR and HOMA-B in the crude and multivariable model.

Results

In the multivariate model, an increase in one SD change in HOM

SUBMITTER: Khalili D 

PROVIDER: S-EPMC9926772 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature