Host metabolome and faecal microbiome shows potential interactions impacted by age and weaning times in calves.

ABSTRACT:

Background

Calves undergo nutritional, metabolic, and behavioural changes from birth to the entire weaning period. An appropriate selection of weaning age is essential to reduce the negative effects caused by weaning-related dietary transitions. This study monitored the faecal microbiome and plasma metabolome of 59 female Holstein calves during different developmental stages and weaning times (early vs. late) and identified the potential associations of the measured parameters over an experimental period of 140 days.

Results

A progressive development of the microbiome and metabolome was observed with significant differences according to the weaning groups (weaned at 7 or 17 weeks of age). Faecal samples of young calves were dominated by bifidobacterial and lactobacilli speci

SUBMITTER: Amin N 

PROVIDER: S-EPMC9926800 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature