Lung morphology impacts the association between ventilatory variables and mortality in patients with acute respiratory distress syndrome.

ABSTRACT:

Background

Acute respiratory distress syndrome (ARDS) patients with different lung morphology have distinct pulmonary mechanical dysfunction and outcomes. Whether lung morphology impacts the association between ventilatory variables and mortality remains unclear. Moreover, the impact of a novel combined ventilator variable [(4×DP) + RR] on morality in ARDS patients needs external validation.

Methods

We obtained data from the Chinese Database in Intensive Care (CDIC), which included adult ARDS patients who received invasive mechanical ventilation for at least 24 h. Patients were further classified into two groups based on lung morphology (focal and non-focal). Ventilatory variables were collected longitudinally within the first four days of ventilation. The primary outcome wa

SUBMITTER: Chen H 

PROVIDER: S-EPMC9926837 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature