Anatomic Biomarkers of Macular Edema Associated with Retinal Vein Occlusion.

ABSTRACT:

Purpose

To assess the relationship between best-corrected visual acuity (BCVA) and anatomic features in patients with macular edema (ME) related to retinal vein occlusion (RVO).

Design

Post hoc analysis of 3 clinical trials, which included verified diagnoses, protocol refractions, and the assessment of OCT and fluorescein angiography (FA) images at a masked reading center.

Participants

Patients diagnosed with RVO-ME.

Methods

Correlation analyses were performed to determine the correlation between BCVA and macular anatomy at baseline and at 12 and 24 weeks and between changes from baseline to 12 and 24 weeks.

Main outcome measures

The correlations between BCVA and central subfield thickness (CST), ellipsoid zone (EZ) integrity, intraretinal fluid (IRF), s

SUBMITTER: Ciulla TA 

PROVIDER: S-EPMC9927025 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature