Dataset Information

An XDR Pseudomonas aeruginosa ST463 Strain with an IncP-2 Plasmid Containing a Novel Transposon Tn6485f Encoding bla_IMP-45 and bla_AFM-1 and a Second Plasmid with Two Copies of bla_KPC-2.

ABSTRACT: The increased carbapenem resistance among Pseudomonas aeruginosa has become a serious health issue worldwide. We reported an extensively drug-resistant (XDR) P. aeruginosa PA30 isolate which belonged to sequence type ST463 and contained an IncP-2 plasmid (pPA30_1) carrying two genes, namely, bla_IMP-45 and bla_AFM-1, which encoded the metallo-β-lactamases AFM-1 and IMP-45, respectively. Additionally, the strain had a plasmid (pPA30_2) with two copies of the bla_KPC-2 genes embedded. The plasmid pPA30_1 was highly similar to the previously reported plasmid pHS17-127, which has the same genetic architecture. This plasmid contained bla_IMP-45, located in a second gene cassette of the integron In786, carried by a Tn1

SUBMITTER: Fang Y

PROVIDER: S-EPMC9927494 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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Dataset Information

An XDR Pseudomonas aeruginosa ST463 Strain with an IncP-2 Plasmid Containing a Novel Transposon Tn6485f Encoding bla_IMP-45 and bla_AFM-1 and a Second Plasmid with Two Copies of bla_KPC-2.

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Dataset Information

An XDR Pseudomonas aeruginosa ST463 Strain with an IncP-2 Plasmid Containing a Novel Transposon Tn6485f Encoding blaIMP-45 and blaAFM-1 and a Second Plasmid with Two Copies of blaKPC-2.

OmicsDI is part of the ELIXIR infrastructure

Tweets

An XDR Pseudomonas aeruginosa ST463 Strain with an IncP-2 Plasmid Containing a Novel Transposon Tn6485f Encoding bla_IMP-45 and bla_AFM-1 and a Second Plasmid with Two Copies of bla_KPC-2.