Cutaneous Surgical Wounds Have Distinct Microbiomes from Intact Skin.

ABSTRACT: Infections are relatively rare following cutaneous surgical procedures, despite the potential for wound exposure to pathogens both during surgery and throughout the healing process. Although gut commensals are believed to reduce the risk of intestinal infections, an analogous role for skin commensals has not been described. In fact, the microbiome of normally healing surgical skin wounds has not yet been profiled using culture-independent techniques. We characterized the wound microbiome in 53 patients who underwent skin cancer surgery and healed without signs or symptoms of infection. A week after surgery, several bacterial species displayed significant differences in relative abundance when compared to control, nonoperated skin from the same patient. The relative abundance of the most co

SUBMITTER: Gupta S 

PROVIDER: S-EPMC9927587 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature