Reducing decoys focuses fighting microglia.
Ontology highlight
ABSTRACT:
SUBMITTER: Duggan MR
PROVIDER: S-EPMC9928165 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Publications
Reducing decoys focuses fighting microglia.
Duggan Michael R MR Walker Keenan A KA
Nature aging 20220715 7
Genetic variation linked to lower levels of soluble ST2, a decoy cytokine receptor for IL-33, may protect against Alzheimer's disease in female <i>APOE</i>ε4 carriers by increasing microglial plaque removal. This discovery advances our understanding of the immune system's role in Alzheimer's disease and underscores the importance of sex-specific disease processes. ...[more]
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