Internet-Based Germline Genetic Testing for Men With Metastatic Prostate Cancer.

ABSTRACT:

Purpose

Germline mutations in DNA repair genes are present in approximately 10% of men with metastatic prostate cancer (mPC), and guidelines recommend genetic germline testing. Notable barriers exist, including access to genetic counseling, insurance coverage, and out-of-pocket costs. The GENTleMEN study was designed to determine the feasibility of an Internet-based, patient-driven germline genetic testing approach for men with mPC.

Patients and methods

In this prospective cohort study, men with mPC provided informed consent via an Internet-based platform and completed a questionnaire including demographics and family cancer history. Supporting medical data were also collected. Genetic testing was performed using the Color Genomics 30-gene targeted panel of cancer predisposi

SUBMITTER: Cheng HH 

PROVIDER: S-EPMC9928882 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature