Desflurane is risk factor for postoperative delirium in older patients' independent from intraoperative burst suppression duration.

ABSTRACT:

Background

Postoperative Delirium (POD) is the most frequent neurocognitive complication after general anesthesia in older patients. The development of POD is associated with prolonged periods of burst suppression activity in the intraoperative electroencephalogram (EEG). The risk to present burst suppression activity depends not only on the age of the patient but is also more frequent during propofol anesthesia as compared to inhalative anesthesia. The aim of our study is to determine, if the risk to develop POD differs depending on the anesthetic agent given and if this correlates with a longer duration of intraoperative burst suppression.

Methods

In this secondary analysis of the SuDoCo trail [ISRCTN 36437985] 1277 patients, older than 60 years undergoing general anesthes

SUBMITTER: Koch S 

PROVIDER: S-EPMC9929347 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature