Changes in brain structure and related functional connectivity during menstruation in women with primary dysmenorrhea.

ABSTRACT:

Background

Neuroimaging studies have identified altered brain structures and functions in women with primary dysmenorrhea (PDM). However, previous studies focused on either structural or functional changes in specific brain regions rather than combining structural and functional analysis. Therefore, this prospective cross-sectional study aimed to investigate the changes in whole brain structure, and functional variation along with structural abnormalities in women with PDM during menstruation.

Methods

In all, 31 patients with PDM (PTs) and 31 healthy controls (HCs) were recruited. Voxel-based morphometry (VBM) and surface-based morphometry (SBM) analyses were applied to investigate structural changes based on high-resolution T1-weighted magnetic resonance images. Functional

SUBMITTER: Liu N 

PROVIDER: S-EPMC9929379 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature