Free-breathing simultaneous water-fat separation and T1 mapping of the whole liver (SWALI) with isotropic resolution using 3D golden-angle radial trajectory.

ABSTRACT:

Background

Conventional liver T1 mapping techniques are typically performed under breath-holding conditions; they have limited slice coverage and often rely on multiple acquisitions. Furthermore, liver fat affects the accuracy of T1 quantification. Therefore, we aim to propose a free-breathing technique for simultaneous water-fat separation and T1 mapping of the whole liver (SWALI) in a single scan.

Methods

The proposed SWALI sequence included an inversion recovery (IR) preparation pulse followed by a series of multiecho three-dimensional (3D) golden-angle radial acquisitions. For each echo time (TE), a series of images containing a mix of water and fat were reconstructed using a sliding window method. For each inversion time (TI), water and fat were separated, and then wate

SUBMITTER: Wang Y 

PROVIDER: S-EPMC9929423 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature