Atopic dermatitis and risk of major neuropsychiatric disorders in children: A population-based cohort study.

ABSTRACT:

Background

Paediatric atopic dermatitis (AD) has been linked to neuropsychiatric comorbidities such as depression, anxiety and attention-deficit/hyperactivity disorder (ADHD). However, longitudinal data are limited, and the effect of AD severity on neuropsychiatric outcomes requires further characterization.

Objectives

To determine the risk of several major neuropsychiatric conditions in children with AD.

Methods

We analysed UK health records data in a population-based cohort study. Each patient <18 years old with AD was matched to up to five unaffected patients on age, practice and index date. Treatments served as proxies for AD severity, which was analysed in a time-updated manner. Outcomes were incident anxiety, depression, bipolar disorder, schizophrenia, ADHD, au

SUBMITTER: Wan J 

PROVIDER: S-EPMC9929490 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature