A challenging case of granulomatosis with polyangiitis with cardiac involvement: a rare case report.

ABSTRACT:

Background

Granulomatosis with polyangiitis (GPA), a systemic antineutrophil cytoplasmic antibody (ANCA) associated vasculitis, is characterized by inflammation of the small arteries, arterioles, and capillaries classically manifesting with glomerulonephritis and necrotizing granulomatous lesions of the upper and lower respiratory tract. With an incidence of approximately 12 cases per one million individuals per year it is an uncommon diagnosis that typically presents as frequent pulmonary and sinus infections; however, if left without definitive treatment progresses to more severe manifestations specifically hemoptysis and hematuria.

Case description

This case report highlights a 15-year-old woman who had both classic and non-classic findings making the diagnosis challengin

SUBMITTER: Shelton A 

PROVIDER: S-EPMC9929659 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature