Dose-response association of handgrip strength and risk of depression: a longitudinal study of 115 601 older adults from 24 countries.

ABSTRACT:

Background

Prior research has solely focused on the association between handgrip strength and risk of depression in single countries or general populations, but more knowledge is required from wider-spread cohorts and target populations.

Aims

This study aimed to investigate the association between handgrip strength and risk of depression using repeated measures in adults aged 50 years and over.

Method

Data on handgrip strength and risk of depression were retrieved from the Survey of Health, Ageing and Retirement in Europe (SHARE) waves 1, 2, 4, 5, 6 and 7, using a hand dynamometer (Smedley, S Dynamometer, TTM) and the EURO-D 12-item scale, respectively. Time-varying exposure and covariates were modelled using both Cox regression and restricted cubic splines.

Result

SUBMITTER: Lopez-Bueno R 

PROVIDER: S-EPMC9929711 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature