Intergenerational impact of childhood trauma on hair cortisol concentrations in mothers and their young infants.

ABSTRACT:

Background

Alterations in stress regulation and function of the hypothalamic-pituitary-adrenal (HPA) axis during infancy may be a risk factor for the development of psychopathology later in life. Maternal childhood trauma, depression, anxiety and stressful life events are individually associated with HPA axis dysregulation. Less is known about their interdependent influence on maternal and infant stress regulation in at risk populations. In a sample of mothers with a history of depressive-, and/or anxiety disorders and their infants we explored if a history of maternal childhood trauma, current depressive and anxiety symptomatology, and recent life events were associated with maternal and infant long-term cortisol levels three months postpartum.

Methods

Data were available o

SUBMITTER: Broeks CW 

PROVIDER: S-EPMC9930158 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature