A narrative review of converging evidence addressing developmental toxicity of pyrethroid insecticides.

ABSTRACT: Pyrethroid insecticides are broadly used in agriculture and household products throughout the world. Exposure to this class of insecticides is widespread, and while generally believed to be safe for use, there is increasing concern regarding their effects on neurodevelopment. Due to the critical roles that molecular targets of pyrethroids play in the regulation of neurodevelopment, particular focus has been placed on evaluating the effects of in utero and childhood pyrethroid exposure on child cognition and behavior. As such, this narrative review synthesizes an assessment of converging study types; we review reports of neonatal pyrethroid levels together with current epidemiological literature that convergently address the risk for developmental toxicity linked to exposure to pyret

SUBMITTER: Elser BA 

PROVIDER: S-EPMC9930199 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature