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Effect of plasma thrombin-antithrombin complex on ischemic stroke: a systematic review and meta-analysis.


ABSTRACT:

Background and objective

Thrombin-antithrombin complex (TAT) is a prethrombotic marker, and its application in ischemic stroke is still uncertain. The purpose of this systematic review and meta-analysis is to evaluate the relationship between plasma TAT and ischemic stroke base on the current evidence.

Methods

A systematic literature search was conducted for searching the relative studies that investigated the association of TAT and ischemic stroke in PubMed, EMBASE, and Cochrane library databases. Mean difference and 95% confidence interval as the effect sizes were synthesized by random effects model in Review Manager (RevMan) Version 5.4. The heterogeneity was investigated using the chi-square test and the possible sources of heterogeneity were explored by sensitivity anal

SUBMITTER: Song P 

PROVIDER: S-EPMC9930276 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature