Comprehensive evaluation of six interventions for hospitalized patients with COVID-19: A propensity score matching study.

ABSTRACT:

Purpose

The purpose of this study was to evaluate the effectiveness of either hydroxychloroquine, triple combination therapy (TCT), favipiravir, dexamethasone, remdesivir, or COVID-19 convalescent plasma (CCP) in comparison with standard-of-care for hospitalized patients with COVID-19 using real-world data from Saudi Arabia.

Patients and methods

A secondary database analysis was conducted using the Saudi Ministry of Health database for patients with COVID-19. Adult (≥18 years) hospitalized patients with COVID-19 between March 2020 and January 2021 were included in the analysis. A propensity score matching technique was used to establish comparable groups for each therapeutic approach. Lastly, an independent t-test and chi-square test were used to compare the matching

SUBMITTER: Alshamrani AA 

PROVIDER: S-EPMC9930407 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature