Bidirectionally connected cores in a mouse connectome: towards extracting the brain subnetworks essential for consciousness.

ABSTRACT: Where in the brain consciousness resides remains unclear. It has been suggested that the subnetworks supporting consciousness should be bidirectionally (recurrently) connected because both feed-forward and feedback processing are necessary for conscious experience. Accordingly, evaluating which subnetworks are bidirectionally connected and the strength of these connections would likely aid the identification of regions essential to consciousness. Here, we propose a method for hierarchically decomposing a network into cores with different strengths of bidirectional connection, as a means of revealing the structure of the complex brain network. We applied the method to a whole-brain mouse connectome. We found that cores with strong bidirectional connections consisted of regions presumably es

SUBMITTER: Kitazono J 

PROVIDER: S-EPMC9930638 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature