Developmental validation of the novel six-dye Goldeneye^TM DNA ID System 35InDel kit for forensic application.

ABSTRACT: Insertion/deletion polymorphisms (InDels) have been treated as a prospective and helpful genetic marker in the fields of forensic human identification, anthropology and population genetics for the past few years. In this study, we developed a six-dye multiplex typing system consisting of 34 autosomal InDels and Amelogenin for forensic application. The contained InDels were specifically selected for Chinese population with the MAF ≥ 0.25 in East Asia, which do not overlap with the markers of Investigator^® DIPplex kit. The typing system was named as Goldeneye^TM DNA ID System 35InDel Kit, and a series of developmental validation studies including repeatability/reproducibility, concordance, accuracy, sensitivity, stability, species specificity and population genetics were

SUBMITTER: Yang Q 

PROVIDER: S-EPMC9930762 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature