Analysis of prognostic factors and construction of prognostic models for triple-positive breast cancer.

ABSTRACT:

Objective

By identifying the clinicopathological characteristics and prognostic influences of patients with triple-positive breast cancer (TPBC) at Xijing Hospital in China compared with those in the United States, this study aims to construct a nomogram model to forecast the overall survival rate (OS) of TPBC patients.

Method

The Surveillance, Epidemiology, and End Results (SEER) database was used to screen 5769 patients as the training cohort, and 191 patients from Xijing Hospital were used as the validation cohort. Cox risk-proportional model was applied to select variables and the nomogram model was constructed based on the training cohort. The performance of the model was evaluated by calculating the C-index and generating calibration plots in the training and validatio

SUBMITTER: Geng A 

PROVIDER: S-EPMC9931069 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature