Orthostatic Hypotension Is a Predictor of Fatigue in Drug-Naive Parkinson's Disease.

ABSTRACT:

Introduction

Fatigue and orthostatic hypotension (OH) are common and disabling nonmotor symptoms (NMSs) of Parkinson's disease (PD), but none of the studies have reported on the longitudinal association between fatigue and OH.

Methods

Drug-naïve PD patients were recruited from a hospital-based cohort and evaluated with the Parkinson Fatigue Scale (PFS), head-up tilt test, Unified PD Rating Scale, Hoehn and Yahr stage, Montreal Cognitive Assessment, Scale for Outcomes in PD-Autonomic (SCOPA-AUT), Beck Depression Inventory (BDI), Beck Anxiety Inventory, PD Sleep Scale, and medications at the baseline and follow-up visits.

Results

A total of 80 patients were included, and the mean ages were 66.6 and 63.8 years in the fatigue and nonfatigue groups, respectively. The preva

SUBMITTER: Ahn JH 

PROVIDER: S-EPMC9931477 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature