Antihypertensive Medication Regimens Used in the Systolic Blood Pressure Intervention Trial.

ABSTRACT:

Background

Describing the antihypertensive medication regimens used in the SPRINT (Systolic Blood Pressure Intervention Trial) would contextualize the standard and intensive systolic blood pressure (SBP) interventions and may inform future implementation efforts to achieve population-wide intensive SBP goals.

Methods

We included SPRINT participants with complete medication data at the prerandomization and 12-month visits. Regimens were categorized by antihypertensive medication class. Analyses were stratified by treatment group (standard goal SBP <140 mm Hg versus intensive goal SBP <120 mm Hg).

Results

Among 7860 participants (83.7% of 9361 randomized), the median number of classes used at the prerandomization visit was 2.0 and 2.0 in the standard and intensive group

SUBMITTER: Derington CG 

PROVIDER: S-EPMC9931643 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature