Optimizing reflex urine cultures: Using a population-specific approach to diagnostic stewardship.

ABSTRACT:

Background

Clinicians and laboratories routinely use urinalysis (UA) parameters to determine whether antimicrobial treatment and/or urine cultures are needed. Yet the performance of individual UA parameters and common thresholds for action are not well defined and may vary across different patient populations.

Methods

In this retrospective cohort study, we included all encounters with UAs ordered 24 hours prior to a urine culture between 2015 and 2020 at 3 North Carolina hospitals. We evaluated the performance of relevant UA parameters as potential outcome predictors, including sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV). We also combined 18 different UA criteria and used receiver operating curves to identify the 5 best-perf

SUBMITTER: Advani SD 

PROVIDER: S-EPMC9931665 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature