The role of [^99mTc]Tc-HFAPi SPECT/CT in patients with malignancies of digestive system: first clinical experience.

ABSTRACT:

Background

Recently, PET/CT imaging with radiolabelled FAP inhibitors (FAPIs) has been widely evaluated in diverse diseases. However, rare report has been published using SPECT/CT, a more available imaging method, with [^99mTc]Tc-labelled FAPI. In this study, we evaluated the potential effect of [^99mTc]Tc-HFAPi in clinical analysis for digestive system tumours.

Methods

This is a single-centre prospective diagnostic efficiency study (Ethic approved No.: XJTU1AF2021LSK-021 of the First Affiliated Hospital of Xi'an Jiaotong University and ChiCTR2100048093 of the Chinese Clinical Trial Register). Forty patients with suspected or confirmed digestive system tumours underwent [^99mTc]Tc-HFAPi SPECT/CT between January and June 2021. For dynamic biodist

SUBMITTER: Jia X 

PROVIDER: S-EPMC9931852 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature