Noise-modulated multistable synapses in a Wilson-Cowan-based model of plasticity.

ABSTRACT: Frequency-dependent plasticity refers to changes in synaptic strength in response to different stimulation frequencies. Resonance is a factor known to be of importance in such frequency dependence, however, the role of neural noise in the process remains elusive. Considering the brain is an inherently noisy system, understanding its effects may prove beneficial in shaping therapeutic interventions based on non-invasive brain stimulation protocols. The Wilson-Cowan (WC) model is a well-established model to describe the average dynamics of neural populations and has been shown to exhibit bistability in the presence of noise. However, the important question of how the different stable regimes in the WC model can affect synaptic plasticity when cortical populations interact has not yet been ad

SUBMITTER: Lea-Carnall CA 

PROVIDER: S-EPMC9931909 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature