Interactive role of miR-29, miR-93, miR-205, and VEGF in salivary adenoid cystic carcinoma.

ABSTRACT:

Objectives

Salivary adenoid cystic carcinoma (SACC) is one of the most common salivary gland tumors in which patients encounter local recurrence and lung metastases. Understanding prognostic biomarkers in SACC is essential for future development in prognosis and treatment. This study aimed to assess the expression level of vascular endothelial growth factor (VEGF) and its potential regulatory microRNAs in SACC for prognostic determination. MATERIAL AND METHODS: The expression of VEGF in SACC samples was assessed using immunohistochemistry. Potential regulatory microRNAs were evaluated using quantitative reverse transcription-polymerase chain reaction. Associations between VEGF and microRNAs expression and clinicopathological parameters were investigated.

Results

VEGF express

SUBMITTER: Bayat P 

PROVIDER: S-EPMC9932236 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature