Incidence and risk factors for medication-related osteonecrosis after tooth extraction in cancer patients-A systematic review.

ABSTRACT:

Objectives

Antiresorptive medication has been reported to be associated with medication-related osteonecrosis of the jaw (MRONJ). This systematic review aims at investigating the incidence of and risk factors for MRONJ after tooth extractions in cancer patients treated with high-dose bisphosphonate and denosumab (BP and DS). MATERIAL AND METHODS: The protocol followed the PRISMA statement list and was registered in PROSPERO. Searches were performed for literature published up to April 2021 in the electronic databases PubMed, Embase, Web of Science, and CINAHL and then supplemented by manual research.

Results

The search process resulted in 771 identified articles, of which seven studies fitted the population, intervention, comparison, and outcome framework. All were observati

SUBMITTER: Schwech N 

PROVIDER: S-EPMC9932256 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature