Long-term fine particular exposure and incidence of frailty in older adults: findings from the Chinese Longitudinal Healthy Longevity Survey.

ABSTRACT:

Background

The association between fine particular matter (PM2.5) and frailty is less studied, and the national burden of PM2.5-related frailty in China is unknown.

Objective

To explore the association between PM2.5 exposure and incident frailty in older adults, and estimate the corresponding disease burden.

Design

Chinese Longitudinal Healthy Longevity Survey from 1998 to 2014.

Setting

Twenty-three provinces in China.

Subjects

A total of 25,047 participants aged ≥65-year-old.

Methods

Cox proportional hazards models were performed to evaluate the association between PM2.5 and frailty in older adults. A method adapted from the Global Burden of Disease Study was used to calculate the PM2.5-related frailty disease burden.

Results

A total of 5,

SUBMITTER: Lv Y 

PROVIDER: S-EPMC9933051 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature