Coronary artery calcium and cystatin C for risk stratification of MACCEs and all-cause death in symptomatic patients.

ABSTRACT:

Objectives

The aim of this study was to examine the independent and joint associations of baseline coronary artery calcium score (CACS) and cystatin C (Cys-C) with the risk of major adverse cardiac and cerebrovascular events (MACCEs) and all-cause death in symptomatic populations.

Methods

The study included 7140 patients with symptom of chest pain who underwent cardiac computerized tomography examinations to measure CACS. All of them had serum Cys-C results. Endpoints were set for MACCEs and all-cause death events.

Results

A total of 7140 participants were followed for a median of 1106 days. A total of 305 patients had experienced MACCEs and 191 patients had experienced all-cause death. CACS ≥ 100 and Cys-C ≥ 0.995 mg/L were independently associated with an increased

SUBMITTER: Luo F 

PROVIDER: S-EPMC9933108 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature