Controlling DNA nanodevices with light-switchable buffers.

ABSTRACT: Control over synthetic DNA-based nanodevices can be achieved with a variety of physical and chemical stimuli. Actuation with light, however, is as advantageous as difficult to implement without modifying DNA strands with photo-switchable groups. Herein, we show that DNA nanodevices can be controlled using visible light in photo-switchable aqueous buffer solutions in a reversible and highly programmable fashion. The strategy presented here is non-invasive and allows the remote control with visible light of complex operations of DNA-based nanodevices such as the reversible release/loading of cargo molecules.

SUBMITTER: Perillat VJ 

PROVIDER: S-EPMC9933455 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature