Dataset Information

Feeding practices and growth patterns of moderately low birthweight infants in resource-limited settings: results from a multisite, longitudinal observational study.

ABSTRACT:

Objectives

To describe the feeding profile of low birthweight (LBW) infants in the first half of infancy; and to examine growth patterns and early risk factors of poor 6-month growth outcomes.

Design

Prospective observational cohort study.

Setting and participants

Stable, moderately LBW (1.50 to <2.50 kg) infants were enrolled at birth from 12 secondary/tertiary facilities in India, Malawi and Tanzania and visited nine times over 6 months.

Variables of interest

Key variables of interest included birth weight, LBW type (combination of preterm/term status and size-for-gestational age at birth), lactation practices and support, feeding profile, birthweight regain by 2 weeks of age and poor 6-month growth outcomes.

Results

Between 13 September 2019 and 27 January 2021, 1114 infants were enrolled, comprising 4 LBW types. 363 (37.3%) infants initiated early breast feeding and 425 (43.8%) were exclusively breastfed to 6 months. 231 (22.3%) did not regain birthweight by 2 weeks; at 6 months, 280 (32.6%) were stunted, 222 (25.8%) underweight and 88 (10.2%) wasted. Preterm-small-for-gestational age (SGA) infants had 1.89 (95% CI 1.37 to 2.62) and 2.32 (95% CI 1.48 to 3.62) times greater risks of being stunted and underweight at 6 months compared with preterm-appropriate-for-gestational age (AGA) infants. Term-SGA infants had 2.33 (95% CI 1.77 to 3.08), 2.89 (95% CI 1.97 to 4.24) and 1.99 (95% CI 1.13 to 3.51) times higher risks of being stunted, underweight and wasted compared with preterm-AGA infants. Those not regaining their birthweight by 2 weeks had 1.51 (95% CI 1.23 to 1.85) and 1.55 (95% CI 1.21 to 1.99) times greater risks of being stunted and underweight compared with infants regaining.

Conclusion

LBW type, particularly SGA regardless of preterm or term status, and lack of birthweight regain by 2 weeks are important risk identification parameters. Early interventions are needed that include optimal feeding support, action-oriented growth monitoring and understanding of the needs and growth patterns of SGA infants to enable appropriate weight gain and proactive management of vulnerable infants.

Trial registration number

NCT04002908.

SUBMITTER: Vesel L

PROVIDER: S-EPMC9933750 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Feeding practices and growth patterns of moderately low birthweight infants in resource-limited settings: results from a multisite, longitudinal observational study.

Vesel Linda L Bellad Roopa M RM Manji Karim K Saidi Friday F Velasquez Esther E Sudfeld Christopher R CR Miller Katharine K Bakari Mohamed M Lugangira Kristina K Kisenge Rodrick R Salim Nahya N Somji Sarah S Hoffman Irving I Msimuko Kingsly K Mvalo Tisungane T Nyirenda Fadire F Phiri Melda M Das Leena L Dhaded Sangappa S Goudar Shivaprasad S SS Herekar Veena V Kumar Yogesh Y Koujalagi M B MB Guruprasad Gowdar G Panda Sanghamitra S Shamanur Latha G LG Somannavar Manjunath M Vernekar Sunil S SS Misra Sujata S Adair Linda L Bell Griffith G Caruso Bethany A BA Duggan Christopher C Fleming Katelyn K Israel-Ballard Kiersten K Fishman Eliza E Lee Anne C C ACC Lipsitz Stuart S Mansen Kimberly L KL Martin Stephanie L SL Mokhtar Rana R RR North Krysten K Pote Arthur A Spigel Lauren L Tuller Danielle E DE Young Melissa M Semrau Katherine E A KEA

BMJ open 20230215 2

<h4>Objectives</h4>To describe the feeding profile of low birthweight (LBW) infants in the first half of infancy; and to examine growth patterns and early risk factors of poor 6-month growth outcomes.<h4>Design</h4>Prospective observational cohort study.<h4>Setting and participants</h4>Stable, moderately LBW (1.50 to <2.50 kg) infants were enrolled at birth from 12 secondary/tertiary facilities in India, Malawi and Tanzania and visited nine times over 6 months.<h4>Variables of interest</h4>Key v ...[more]

PMID: 36792338

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Dataset Information

Feeding practices and growth patterns of moderately low birthweight infants in resource-limited settings: results from a multisite, longitudinal observational study.

Objectives

Design

Setting and participants

Variables of interest

Results

Conclusion

Trial registration number

Publications

Feeding practices and growth patterns of moderately low birthweight infants in resource-limited settings: results from a multisite, longitudinal observational study.

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