Ontology highlight
ABSTRACT:
SUBMITTER: Zhou P
PROVIDER: S-EPMC9933850 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Immunity 20230216 3
Pan-betacoronavirus neutralizing antibodies may hold the key to developing broadly protective vaccines against novel pandemic coronaviruses and to more effectively respond to SARS-CoV-2 variants. The emergence of Omicron and subvariants of SARS-CoV-2 illustrates the limitations of solely targeting the receptor-binding domain (RBD) of the spike (S) protein. Here, we isolated a large panel of broadly neutralizing antibodies (bnAbs) from SARS-CoV-2 recovered-vaccinated donors, which targets a conse ...[more]