Conservation and Expansion of Transcriptional Factor Repertoire in the <i>Fusarium oxysporum</i> Species Complex.

ABSTRACT: The Fusarium oxysporum species complex (FOSC) includes both plant and human pathogens that cause devastating plant vascular wilt diseases and threaten public health. Each F. oxysporum genome comprises core chromosomes (CCs) for housekeeping functions and accessory chromosomes (ACs) that contribute to host-specific adaptation. This study inspected global transcription factor profiles (TFomes) and their potential roles in coordinating CCs and ACs functions to accomplish host-specific pathogenicity. Remarkably, we found a clear positive correlation between the sizes of TFome and proteome of an organism, and FOSC TFomes are larger due to the acquisition of ACs. Among a total of 48 classified TF families, 14 families involved in transcription/translation regulations and cell cycle

SUBMITTER: Yu H 

PROVIDER: S-EPMC9934661 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature