Broadband aperiodic components of local field potentials reflect inherent differences between cortical and subcortical activity.

ABSTRACT: Information flow in brain networks is reflected in intracerebral local field potential (LFP) measurements that have both periodic and aperiodic components. The 1/f^χ broadband aperiodic component of the power spectra has been shown to track arousal level and to correlate with other physiological and pathophysiological states, with consistent patterns across cortical regions. Previous studies have focused almost exclusively on cortical neurophysiology. Here we explored the aperiodic activity of subcortical nuclei from the human thalamus and basal ganglia, in relation to simultaneously recorded cortical activity. We elaborated on the FOOOF (fitting of one over f) method by creating a new parameterization of the aperiodic component with independent and more easily interpretable para

SUBMITTER: Bush A 

PROVIDER: S-EPMC9934688 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature