Evaluating the role of time in range as a glycemic target during short-term intensive insulin therapy in patients with newly diagnosed type 2 diabetes.

ABSTRACT:

Background

Tight glycemic control during short-term intensive insulin therapy (SIIT) is critical for inducing diabetes remission in patients with newly diagnosed type 2 diabetes (T2D). This work aimed to investigate the role of time in range (TIR) during SIIT as a novel glycemic target by predicting clinical outcomes.

Methods

SIIT was given to 116 patients with newly diagnosed T2D, with daily eight-point capillary glucose monitored. Glycemic targets (fasting/premeal glucose, 3.9-6.0 mmol/L; 2 h postprandial blood glucose, 3.9-7.8 mmol/L) were achieved and maintained for 2 weeks. TIR_PIR was calculated as the percentage of glucose points within these glycemic targets during the maintenance period and was compared to TIR_{3.9-7.8mmol/L} and TIR_3.9-10.0mm

SUBMITTER: Liu L 

PROVIDER: S-EPMC9934958 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature