Changes in fasting blood glucose status and incidence of cardiovascular disease: The China-PAR project.

ABSTRACT:

Background

The effect of long-standing prediabetes or its transition on incident cardiovascular disease (CVD) is unclear. This study aimed to evaluate the association of changes in fasting blood glucose (FBG) status with the risk of developing CVD.

Methods

This research included 12 145 Chinese adults aged 35-74 years and free from diabetes mellitus (DM) at baseline. Study participants were cross-classified into six categories according to glucose at the first (1998-2001) and the second visit after 8 years: normal fasting glucose (NFG; 50-99 mg/dl), impaired FBG (IFG; 100-125 mg/dl), and DM. Cox proportional hazard regression model was used to estimate the hazard ratio (HR) and 95% confidence interval (CI) for CVD associated with transition of glucose status.

Results

D

SUBMITTER: Tong Y 

PROVIDER: S-EPMC9934960 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature