Contrast media timing optimization for coronary CT angiography: a retrospective validation study in swine.

ABSTRACT:

Objectives

The objective was to retrospectively develop a protocol in swine for optimal contrast media timing in coronary CT angiography (CCTA).

Methods

Several dynamic acquisitions were performed in 28 swine (55 ± 24 kg) with cardiac outputs between 1.5 and 5.5 L/min, for 80 total acquisitions. The contrast was injected (1mL/kg, 5mL/s, Isovue 370), followed by dynamic scanning of the entire aortic enhancement curve, from which the true peak time and aortic and coronary enhancements were recorded as the reference standard. Each dataset was then used to simulate two different CCTA protocols-a new optimal protocol and a standard clinical protocol. For the optimal protocol, the CCTA was acquired after bolus tracking-based trigging using a variable time delay of one-half the con

SUBMITTER: Hubbard L 

PROVIDER: S-EPMC9935703 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature